產(chǎn)品描述

塔望科技提供全系列的動物實驗用低/高氧控制產(chǎn)品，包括恒定濃度控制的低氧動物箱、高氧動物箱、可編程的間歇氧濃度控制系統(tǒng)、帶緩沖艙的手套低氧箱等。整套間歇氧氧實驗箱裝置主要由氧氣控制器和動物實驗箱兩部分組成。另可提供多種不同的氣體控制器，滿足不同實驗O2、CO2、NO、CO、O3等氣體濃度控制的需求。

ProOx-100動物間歇低氧實驗系統(tǒng)可以控制動物實驗箱內(nèi)持續(xù)低氧的環(huán)境，用以制造相關(guān)的間歇低氧實驗?zāi)Ｐ?。用戶可自由設(shè)置所需要的濃度和實驗持續(xù)時間，所有的設(shè)置通過控制主機觸摸屏完成，人性化設(shè)計，操作簡便。

ProOx-100動物間歇低氧實驗系統(tǒng)監(jiān)測指標全面，動物低氧艙內(nèi)具有集成化的傳感器模塊，內(nèi)置溫度、濕度、氧氣、二氧化碳傳感器。可以實時監(jiān)測動物低氧艙內(nèi)的環(huán)境。系統(tǒng)通過閉環(huán)反饋控制，根據(jù)動物低氧艙內(nèi)的氧濃度實時反饋控制，使動物實驗數(shù)據(jù)更準確。Ox-100動物低氧實驗系統(tǒng)具有優(yōu)良的控制性能，持續(xù)低氧實驗時，氧濃度的誤差為0.1%。

如需高氧實驗，請選擇型號Ox-100HE。

產(chǎn)品特點及參數(shù)

1. 為動物間歇低氧實驗?zāi)Ｐ偷慕⑻峁┓€(wěn)定的低氧環(huán)境

2. 按照設(shè)定氣體濃度自動配比氣體，無需在箱體外混合比例氣體，實驗氧濃度的準確，節(jié)省氣源

3. 艙體采用全透明PMMA材質(zhì)，防止由于光線影響動物生物節(jié)律

4. 7英寸大屏觸摸屏控制，人性化界面，操作簡單

5. 監(jiān)測參數(shù)：溫度、濕度、氧氣O2濃度、二氧化碳濃度

6. 控制精度：±0.1%

7. 非色散紅外（NDIR）二氧化碳傳感器，測量范圍：0～5000ppm

8. 進口電化學(xué)氧氣O2濃度檢測器，測量范圍：0-25%vol，線性度好，檢測準確、使用壽命長。具有溫度補償機制

9. 溫度檢測：進口高精度溫度傳感器

10. 氧氣濃度變化動態(tài)曲線，直觀了解氧氣濃度變化的過程

11. 具有定時功能，實驗完成，自動恢復(fù)常氧狀態(tài)，并伴有聲音提示

12. 氧氣濃度自動校準：通過控制器對傳感器快速校準

13. *的氣體混合及循環(huán)機制，保證箱體內(nèi)氣體濃度的均一

14. 高性能電磁閥，性能穩(wěn)定，超長壽命

15. 艙體尺寸有多種選擇，可靈活搭配。也可根據(jù)實驗要求進行定制

ProOx-100動物間歇低氧實驗系統(tǒng)多功能控制

可進行間歇低氧實驗（CIH）、急性缺氧實驗、慢性缺氧實驗、高氧/低氧交替實驗

應(yīng)用領(lǐng)域

肺動脈高壓、腎臟疾病研究、腫瘤研究、心血管疾病研究、視網(wǎng)膜病變、運動醫(yī)學(xué)研究、OSAHS、腦發(fā)育與神經(jīng)生物學(xué)、干細胞研究、醫(yī)學(xué)研究等

型號說明

艙體型號（可選擇不同尺寸的低氧艙）

引用文獻

[1] Drekolia M K, Mettner J, Wang D, et al. Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation[J]. Cell Metabolism (IF 30.9), 2025.

[2] Wu L W, Chen M, Jiang C Y, et al. Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension[J]. Advanced Science (IF 14.1), 2025: e08995.

[3] Lei R, Gu M, Li J, et al. Lipoic acid/trometamol assembled hydrogel as injectable bandage for hypoxic wound healing at high altitude[J]. Chemical Engineering Journal (IF 13.4), 2024, 489: 151499.

[4] Li Z, Li H, Qiao W, et al. Multi-omics dissection of high TWAS-active endothelial pathogenesis in pulmonary arterial hypertension: bridging single-cell heterogeneity, machine learning-driven biomarkers, and developmental reprogramming[J]. International Journal of Surgery (IF 10.1), 10.1097.

[5] Pei Y, Huang L, Wang T, et al. Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury[J]. Materials Today Advances (IF 10), 2023, 17: 100349.

[6] Wang Q, Liu J, Li R, et al. Macrophage κ-opioid receptor inhibits hypoxic pulmonary hypertension progression and right heart dysfunction via an SCD1-dependent anti-inflammatory response[J]. Genes & Diseases (IF 9.4), 2025: 101604.

[7] Wang Y, Zhang R, Chen Q, et al. PPARγ Agonist Pioglitazone Prevents Hypoxia-induced Cardiac Dysfunction by Reprogramming Glucose Metabolism[J]. International Journal of Biological Sciences, 2024, 20(11): 4297.

[8] Wang Y, Shen P, Wu Z, et al. Plasma Proteomic Profiling Reveals ITGA2B as a key regulator of heart health in high-altitude settlers[J]. Genomics, Proteomics & Bioinformatics, 2025: qzaf030.

[9] Lan Y, Zhao S, Song Y, et al. Physicochemical properties of selenized quinoa protein hydrolysate and its regulatory effects on neuroinflammation and gut microbiota in hypoxic mice[J]. Journal of Future Foods, 2025.

[10] Pan Z, Yao Y, Liu X, et al. Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation[J]. Cell Death Discovery, 2024, 10(1): 459.

[11] Zhou Y, Ni Z, Liu J, et al. Gut Microbiota‐Associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High‐Altitude: Gut Microbiota and Associated Metabolites Impart Heart Health in Plateau[C]//Exploration. 2025: 20240332.

[12] Li C, Zhao Z, Jin J, et al. NLRP3-GSDMD-dependent IL-1β Secretion from Microglia Mediates Learning and Memory Impairment in a Chronic Intermittent Hypoxia-induced Mouse Model[J]. Neuroscience, 2024, 539: 51-65.

[13] Yang W, Li M, Ding J, et al. High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen[J]. Elife, 2024, 12: RP87496.

[14] You Z, Huang Q, Zeng L, et al. Rab26 promotes hypoxia-induced hyperproliferation of PASMCs by modulating the AT1R-STAT3-YAP axis[J]. Cellular and Molecular Life Sciences, 2025, 82(1): 1-16.

[15] Pei C, Shen Z, Wu Y, et al. Eleutheroside B Pretreatment Attenuates Hypobaric Hypoxia‐Induced High‐Altitude Pulmonary Edema by Regulating Autophagic Flux via the AMPK/mTOR Pathway[J]. Phytotherapy Research, 2024, 38(12): 5657-5671.

[16] Duan H, Han Y, Zhang H, et al. Eleutheroside B Ameliorates Cardiomyocytes Necroptosis in High-Altitude-Induced Myocardial Injury via Nrf2/HO-1 Signaling Pathway[J]. Antioxidants, 2025, 14(2): 190.

[17] Song J, Zheng J, Li Z, et al. Sulfur dioxide inhibits mast cell degranulation by sulphenylation of galectin-9 at cysteine 74[J]. Frontiers in Immunology, 2024, 15: 1369326.

[18] Jia N, Shen Z, Zhao S, et al. Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr. etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway[J]. International Immunopharmacology, 2023, 121: 110423.

[19] Huang Q, Han X, Li J, et al. Intranasal Administration of Acetaminophen-Loaded Poly (lactic-co-glycolic acid) Nanoparticles Increases Pain Threshold in Mice Rapidly Entering High Altitudes[J]. Pharmaceutics, 2025, 17(3): 341.

[20] Wu Y, Tang Z, Du S, et al. Oral quercetin nanoparticles in hydrogel microspheres alleviate high-altitude sleep disturbance based on the gut-brain axis[J]. International Journal of Pharmaceutics, 2024, 658: 124225.

[21] Zhou Z, Zhao Q, Huang Y, et al. Berberine ameliorates chronic intermittent hypoxia‐induced cardiac remodelling by preserving mitochondrial function, role of SIRT6 signalling[J]. Journal of Cellular and Molecular Medicine, 2024, 28(12): e18407.

[22] Shang W, Huang Y, Xu Z, et al. The impact of a high-carbohydrate diet on the cognitive behavior of mice in a low-pressure, low-oxygen environment[J]. Food & Function, 2025, 16(3): 1116-1129.

[23] Pei C, Jia N, Wang Y, et al. Notoginsenoside R1 protects against hypobaric hypoxia-induced high-altitude pulmonary edema by inhibiting apoptosis via ERK1/2-P90rsk-BAD ignaling pathway[J]. European Journal of Pharmacology, 2023, 959: 176065.

[24] Xie L, Wu Q, Huang H, et al. Neuroregulation of histamine of circadian rhythm disorder induced by chronic intermittent hypoxia[J]. European Journal of Pharmacology, 2025: 177662.

[25] Ding Y, Liu W, Zhang X, et al. Bicarbonate-Rich Mineral Water Mitigates Hypoxia-Induced Osteoporosis in Mice via Gut Microbiota and Metabolic Pathway Regulation[J]. Nutrients, 2025, 17(6): 998.

[26] Gu N, Shen Y, He Y, et al. Loss of m6A demethylase ALKBH5 alleviates hypoxia-induced pulmonary arterial hypertension via inhibiting Cyp1a1 mRNA decay[J]. Journal of Molecular and Cellular Cardiology, 2024.

[27] Luan X, Zhu D, Hao Y, et al. Qibai Pingfei Capsule ameliorated inflammation in chronic obstructive pulmonary disease (COPD) via HIF-1 α/glycolysis pathway mediated of BMAL1[J]. International Immunopharmacology, 2025, 144: 113636.

[28] Jiang H, Lu C, Wu H, et al. Decreased cold‐inducible RNA‐binding protein (CIRP) binding to GluRl on neuronal membranes mediates memory impairment resulting from prolonged hypobaric hypoxia exposure[J]. CNS Neuroscience & Therapeutics, 2024, 30(9): e70059.

[29] Chang P, Xu M, Zhu J, et al. Pharmacological Inhibition of Mitochondrial Division Attenuates Simulated High‐Altitude Exposure‐Induced Memory Impairment in Mice: [30] Involvement of Inhibition of Microglia‐Mediated Synapse Elimination[J]. CNS Neuroscience & Therapeutics, 2025, 31(6): e70473.

[30] Liu C, Qu D, Li C, et al. miR‐448‐3p/miR‐1264‐3p Participates in Intermittent Hypoxic Response in Hippocampus by Regulating Fam76b/hnRNPA2B1[J]. CNS Neuroscience & Therapeutics, 2025, 31(2): e70239.

[31] Wu L W, Chen M, Jiang D J, et al. TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells[J]. Respiratory Research, 2025, 26(1): 202.

[32] Xie L, Wu Q, Huang H, et al. Neuroregulation of histamine of circadian rhythm disorder induced by chronic intermittent hypoxia[J]. European Journal of Pharmacology, 2025: 177662.

[33] Cai S, Li Z, Bai J, et al. Optimized oxygen therapy improves sleep deprivation-induced cardiac dysfunction through gut microbiota[J]. Frontiers in Cellular and Infection Microbiology, 2025, 15: 1522431.

[34] Wang X, Xie Y, Niu Y, et al. CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting[J]. Frontiers in Cellular Neuroscience, 2023, 17: 1189348.

[35] He Y, Wang Y, Duan H, et al. Pharmacological targeting of ferroptosis in hypoxia-induced pulmonary edema: therapeutic potential of ginsenoside Rg3 through activation of the PI3K/AKT pathway[J]. Frontiers in Pharmacology, 2025, 16: 1644436.

[36] Guo Y, Qin J, Sun R, et al. Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice[J]. Biological Research, 2024, 57.

[37] Liu L, Zhang J, Song S, et al. Paraventricular nucleus neurons: important regulators of respiratory movement in mice with chronic intermittent hypoxia[J]. Annals of Medicine, 2025, 57(1): 2588664.

[38] Ma Q, Ma J, Cui J, et al. Oxygen enrichment protects against intestinal damage and gut microbiota disturbance in rats exposed to acute high-altitude hypoxia[J]. Frontiers in Microbiology, 2023, 14.

[39] Lan J, Lin J, Guo Y, et al. Sequencing and bioinformatics analysis of exosome-derived miRNAs in mouse models of pancreatic injury induced by OSA[J]. Frontiers in Physiology, 2025, 16: 1712442.

[40] Feng X, Li C, Zhang W, et al. Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions[J]. Scientific Reports, 2025, 15(1): 36049.

[41] Yao Y, Chen Y, Li Y, et al. TGM2 Enhances Hypobaric Hypoxia-mediated Brain Injury Via Regulating NLRP3/GSDMD Signaling[J]. Neurochemical Research, 2025, 50(6): 1-11.

[42] Yang A, Guo L, Zhang Y, et al. MFN2-mediated mitochondrial fusion facilitates acute hypobaric hypoxia-induced cardiac dysfunction by increasing glucose catabolism and ROS production[J]. Biochimica et Biophysica Acta (BBA)-General Subjects, 2023: 130413.

[43] Chu H, Jiang W, Zuo N, et al. Astrocyte activation: A key mediator underlying chronic intermittent hypoxia-induced cognitive dysfunction[J]. Sleep Medicine, 2025: 106692.

[44] Xu A, Huang F, Chen E, et al. Hyperbaric oxygen therapy attenuates heatstroke-induced hippocampal injury by inhibiting microglial pyroptosis[J]. International Journal of Hyperthermia, 2024, 41(1): 2382162.

[45] Zhang Z, Zheng X, He Y, et al. Hyperbaric oxygen ameliorates neuroinflammation in heat-stressed BV-2 microglial cells: potential involvement of EAAT2 regulation[J]. International Journal of Hyperthermia, 2025, 42(1): 2583133.

[46] Jinyu F, Huaicun L, Yanfei Z, et al. Nogo-A Protein Mediates Oxidative Stress and Synaptic Damage Induced by High-altitude Hypoxia in the Rat Hippocampus[J]. 2024.

[47] Su L, Ni T, Fan R, et al. An attention to the effect of intravitreal injection on the controls of oxygen-induced retinopathy mouse model[J]. Experimental Eye Research, 2024, 248: 110094.

[48] Xu Y, Xu J, Li J, et al. Interplay of HIF-1α, SMAD2, and VEGF signaling in hypoxic renal environments: impact on macrophage polarization and renoprotection[J]. Renal Failure, 2025, 47(1): 2561784.

[49] Zhang D, Bian W, Gao Z. Impact of Obstructive Sleep Apnea on Endometrial Function in Female Rats: Mechanism Exploration[J]. Nature and Science of Sleep, 2025: 2485-2499.

[50] Zhang N, Wei F, Ning S, et al. PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats[J]. Journal of Cardiovascular Translational Research, 2024: 1-13.

[51] Zhang Y, Zhang A, Yang J, et al. Hypoxic Mesenchymal Stem Cell Exosome‐Derived SLC25A3 Ameliorates Bronchopulmonary Dysplasia by Modulating Macrophage Polarization and Oxidative Stress[J]. Cell Biochemistry and Function, 2025, 43(12): e70152.

[52] Lan J, Wang Y, Liu C, et al. Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea[J]. BMC Pulmonary Medicine, 2025, 25(1): 158.

[53] Zhang L, Liu X, Wei Q, et al. Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p[J]. Mammalian Genome, 2023, 34(1): 76-89.

[54] Wei J, Hu M, Chen X, et al. Hypobaric Hypoxia Aggravates Renal Injury by Inducing the Formation of Neutrophil Extracellular Traps through the NF-κB Signaling Pathway[J]. Current Medical Science, 2023: 1-9.

[55] Zhang L, Li J, Wan Q, et al. Intestinal stem cell-derived extracellular vesicles ameliorate necrotizing enterocolitis injury[J]. Molecular and Cellular Probes, 2025, 79: 101997.

[56] Liao Y, Ke B, Long X, et al. Abnormalities in the SIRT1-SIRT3 axis promote myocardial ischemia-reperfusion injury through ferroptosis caused by silencing the PINK1/Parkin signaling pathway[J]. BMC Cardiovascular Disorders, 2023, 23(1): 582.

[57] Wang M, Wen W, Chen Y, et al. TRPC5 channel participates in myocardial injury in chronic intermittent hypoxia[J]. Clinics, 2024, 79: 100368.

[58] Li J, Ye J. Chronic intermittent hypoxia induces cognitive impairment in Alzheimer’s disease mouse model via postsynaptic mechanisms[J]. Sleep and Breathing, 2024: 1-9.

[59] Binbin L I, Haizhen L I, Houhuang C, et al. Utilizing Hyperbaric Oxygen Therapy to Improve Cognitive Function in Patients With Alzheimer’s Disease by Activating Autophagy-Related Signaling Pathways[J]. Physiological Research, 2025, 74(1): 141.

[60] Han J, Wang L, Wang L, et al. 5-Hydroxytryptamine Limits Pulmonary Arterial Hypertension Progression by Regulating Th17/Treg Balance[J]. Biological and Pharmaceutical Bulletin, 2025, 48(5): 555-562.

[61] Nan L, Kaisi F, Mengzhen Z, et al. miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis[J]. Pediatric Surgery International, 2024, 40(1): 63.

[62] Liu B, Zheng W, Tang C, et al. Scutellarein-containing novel formula attenuates hypoxia through inhibiting apoptosis[J]. 2025.

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